Copaiba oil-resin is widely used in traditional medicine due to its anti-inflammatory, healing, and antiseptic activities. In a double-blind placebo-controlled clinical trial, there was a highly significant decrease in the surface affected with acne in the areas treated with the 1.0% copaiba essential oil preparation. Read the abstract here.
A. G. da Silva et al., “Application of the essential oil from copaiba (Copaifera langsdori Desf.) for acne vulgaris: a double-blind, placebo-controlled clinical trial,” Altern. Med. Rev. J. Clin. Ther., vol. 17, no. 1, pp. 69–75, Mar. 2012.